Extended Data Fig. 1: Phenotypic distribution of hematopoietic cells in BM and PB of patients with VEXAS syndrome.
From: Mechanisms of hematopoietic clonal dominance in VEXAS syndrome
a-d, Percentage of cells within hematopoietic cells (a), myeloid cells (b), lymphoid cells (c) and HSPCs (d) from BM aspirates of patients with VEXAS syndrome and age-matched controls (n = 19, 7). Mean ± s.e.m. Data on age-matched reference controls from59 are shown. e-h, Percentage of cells within total circulating hematopoietic cells (e), myeloid cells (f), lymphoid cells (g) and HSPCs (h) in the blood of patients with VEXAS syndrome and age-matched controls (n = 19, 7). Mean ± s.e.m. i, Number of myeloid, erythroid, megakaryocytic, NK and preT cells obtained upon in vitro differentiation of HSPCs from two patients with VEXAS syndrome (n = 2) or age-matched controls (n = 3). For all panels: Mann-Whitney test.
