Extended Data Fig. 2: Forest plot of subgroup analysis for overall survival according to baseline characteristics and selected prognostic factors.

HR and associated 95% CI were estimated using Cox proportional-hazards models with Breslow’s method of tie handling. CI, confidence interval; ECOG, Eastern Cooperative Oncology Group; HER2, human epidermal growth factor receptor 2; HR, hazard ratio; IHC, immunohistochemistry; OS, overall survival; PD-L1, programmed death-ligand 1; ref, reference subgroup.