Extended Data Fig. 6: Mean fold increase of key inflammatory cytokines in the CSF from Day 0 through Day 28 across all patients by dose level.

Mean fold increase of cytokines interferon-gamma (IFNg), interleukin-2 (IL2), interleukin-6 (IL6), and tumor necrosis factor alpha (TNFa) in the CSF from Day 0 through Day 28 across all patients by dose level (n = 6 per dose level). Data are presented as mean values +/− SEM.