Extended Data Fig. 1: Overview of biomarker analyses and associations between DFS and treatment arm by patient population.

a. Overview of biomarker analyses completed. b. Associations between DFS and treatment arm in all treated patients, the CD8 digital IHC-evaluable population and the CD8 digital IHC non-evaluable population. Shaded areas indicate 95% CI. c. Associations between DFS and treatment arm in all treated patients, the RNA-seq–evaluable population and the RNA-seq non-evaluable population. Shaded areas indicate 95% CI. d. Associations between DFS and treatment arm in all treated patients, the WES-evaluable population and the WES non-evaluable population. Shaded areas indicate 95% CI.