Fig. 2: Liver enzymes and specific gamma interferon ELISpots for capsid and transgene epitope libraries.
From: Dual-vector rAAVrh8 gene therapy for GM2 gangliosidosis: a phase 1/2 trial

Normal ranges are indicated for liver enzymes in dotted lines. Positive and negative ELISpot responses are denoted by red and blue shading, respectively. Complete immune response data are presented in the companion publication12. ALT, alanine transaminase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; IFNɣ, interferon-ɣ; M, male; NA, not applicable (no sample collected); yr, years.