Extended Data Fig. 6: Depth and duration of response by TROP2 expression.

a, b, waterfall plot depicting the maximum change from baseline in target lesion size in patients with TROP2 H-score of ≤ 200 (a) and TROP2 H-score of > 200 (b); c, d, spider plots showing the percentage change from baseline in the sum of the longest diameters (SLD) of target lesions over time in patients with TROP2 H-score of ≤ 200 (c) and TROP2 H-score of > 200 (d). Each line represents an individual patient; timepoints (x-axis) show scheduled assessments; the y-axis indicates SLD change (%). The end of each line is marked with a square to indicate treatment discontinuation (last assessment before stopping treatment for any reason) or a triangle to indicate treatment ongoing (patient still receiving therapy at the data cutoff).