Extended Data Table 1 Subgroup efficacy in cohort 1A and cohort 1B grouped by PD-L1 expression among TROP2 low or high-expression population

From: First-line sacituzumab tirumotecan with tagitanlimab in advanced non-small-cell lung cancer: a phase 2 trial

  1. Data cutoff date: May 27, 2024.
  2. aTROP2 expression was assessed at a central lab using the EPR20043 antibody.
  3. bPD-L1 expression was assessed at a central lab with PD-L1 IHC 22C3 pharmDx.
  4. cIncluding confirmed PR/CR and response pending confirmation. ORR was calculated based on the full analysis set population.
  5. dDCR was defined as BOR of CR + PR + SD ≥ 6 weeks. DCR was calculated based on the full analysis set population.
  6. PD-L1, programmed cell death ligand 1; TPS, tumor proportion score; ORR, objective response rate; DCR, disease control rate.
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