Fig. 5: Physiological systems, tissue and cell-type enrichment analyses for uncoupling loci and general body fat percentage loci.

DEPICT results were based on summary statistics generated from the association analyses of the 266 lead single-nucleotide polymorphisms (SNPs) with BFP. Tissues enriched after correction for multiple testing at significance threshold (FDR < 0.05) are highlighted in bright blue. The dashed line represents the nominal significance level (P < 0.05). For full results, see Supplementary Table 15.