Extended Data Fig. 2: Sex-specific associations of genetic risk scores with anthropometric and cardiometabolic traits in the UK Biobank. | Nature Medicine

Extended Data Fig. 2: Sex-specific associations of genetic risk scores with anthropometric and cardiometabolic traits in the UK Biobank.

From: Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities

Extended Data Fig. 2

A. Estimated per 10 allele change effect sizes of GRS–trait associations in UK Biobank European ancestry population for GRSuncoupling (men in light magenta, women in dark magenta) and GRSBFP (men in light blue, women in dark blue). B-C. Estimated per 10 allele change effect sizes of GRS–trait associations in UK Biobank European ancestry population for each cluster-specific GRS (GRS 1–8, men in light magenta, women in dark magenta). The dashed circles are labeled ‘0’, indicating no association between each GRS and the trait. Points outside the circle represent positive GRS–trait associations, while those inside represent negative associations.

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