Extended Data Fig. 2: Supplementary data for ratiometric analysis.

a, Example of the raw Raman spectra used for ratiometric analysis acquired in metastatic tissue (magenta) and in a contralateral position in healthy tissue (cyan). b Derivative of Raman spectra for cancer free (cyan) and cancer invade (magenta) regions in the high-wavenumber (HW) range. For display reasons, the plot shows 1 measurement out of 5 for every implant position.