Extended Data Table 1 Comparison of CellNEST with other latest state-of-the-art methods for CCC detection

From: CellNEST reveals cell–cell relay networks using attention mechanisms on spatial transcriptomics

  1. Comparison of CellNEST with other latest state-of-the-art methods for CCC detection based on: (1) prior requirements beyond a ligand–receptor (LR) database, (2) whether the output returns name of the ligand–receptor pairs and (3) at single-cell resolution, (4) an unsupervised training strategy, (5) how far CCC is detected on the tissue, (6) integration of spatial distance, (7) relay-network capability, and (8) publication or release year. CellNEST was the only method capable of every listed feature, including CellNEST’s unique ability to identify and reconstruct relay networks.