Extended Data Fig. 6: Automatic task performance in combined cohort does not recover after one month of retraining.
From: The role of motor cortex in motor sequence execution depends on demands for flexibility
a, Performance in the AUTO task from the 1st week of training (early), 7 days before the lesion (pre-lesion), 7 days after the lesion (post-lesion) and 1 month following lesion (late) in the combined task (green, n = 7) and AUTO-only (purple, n = 6) cohorts. Error bars denote s.e.m. b, Average performance, measured as the fraction of successful trials, from time conditions (pre, post and late) across rats (n = 6 for AUTO-only and n = 7 for combined cohorts), represented as individual lines. c–e, Kinematic metrics plotted in the week before lesion (pre), the week after lesion (post) and a month following lesion (late). c, Trial time. d, Trial speed. e, Forelimb trajectory correlation. Lines denote individual rats (n = 6 for AUTO-only and n = 7 for combined cohorts). *P < 0.05, **P < 0.01, ***P < 0.001, two-sided paired (within cohort) or unpaired (across cohorts) t-test.
