Extended Data Fig. 2: Dopamine responses are highly correlated across recording sites. | Nature Neuroscience

Extended Data Fig. 2: Dopamine responses are highly correlated across recording sites.

From: Prospective contingency explains behavior and dopamine signals during associative learning

Extended Data Fig. 2

(a) Averaged dopamine axonal responses to Odor A during rewarded trials for both Deg group and CuedRew group, depicted for Phase I session 5 and Phase II session 10 across all recorded sites. (b) Correlation matrix for averaged dopamine responses to Odor A during rewarded trials, comparing across sites from the Deg groups during sessions 5 and 10. Cosine similarity was calculated by averaging z-scored responses across trials within animals, then across animals and then computing the cosine similarity between each recording site. For some olfactory tubercule recording sites there was no discernable signal and were thus excluded from this analysis. Sample size (n) report per site. (c) Population average dopamine responses to Odor A in rewarded trials across sessions 1 to 10 for both Deg and CuedRew groups, detailing the changes in response through Phase I and Phase II.

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