Extended Data Fig. 3: Noradrenergic activation of the BLA does not increase CREB or pCREB protein levels within the ventral blade of the DG.

NE (1.0 µg in 0.2 µl) was administered unilaterally into one BLA and saline into the other BLA, counterbalanced across animals, immediately after training on the dual-event inhibitory avoidance task. NE administration did not affect CREB or pCREB protein levels within the ventral blade of the DG granule cell layer 3 h later. Protein levels are normalized to the saline-treated hemisphere (mean + s.e.m.) (n = 7, paired Student’s t-test: CREB: t6 = 1.43, P = 0.20; pCREB: t6 = 1.01, P = 0.35).