Extended Data Fig. 5: Interface between domain III of apo-RF3 and domain I of RF1 in structure I-B.
From: The ribosome termination complex remodels release factor RF3 and ejects GDP
a, In apo-RF3, the residues for which mutation to alanine reduces the rate of GDP exchange are shown with yellow spheres. These residues form the interface with RF1. Mutation of the residues shown with light blue spheres has a mild effect on the rate of GDP exchange. Note that residue E516 does not interact with RF1. b, The Cα and Cβ atoms of residue N510 contribute to the interface with RF1, while the hydrophilic groups of N510 are not interacting with RF1.
