Extended Data Fig. 2: Clustering of PGCs by sex. | Nature Structural & Molecular Biology

Extended Data Fig. 2: Clustering of PGCs by sex.

From: Temporal and regional X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencing

Extended Data Fig. 2

(A) Pseudotime representation of the scRNA-seq data based on the first principal component for XX females (pink), XO females (red), and XY males (blue). (B) Level of Xist expression and degree of reactivation in each single cell. Each dot represents a single cell. Most female soma cells exhibit high Xist expression and a low number of biallelically expressed genes. Genes with RPRT expression < 4 were considered to be unexpressed.

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