Extended Data Fig. 2: Sanger sequencing and STR profiles of the 8 affected families.
From: Maternal ELL3 loss-of-function leads to oocyte aneuploidy and early miscarriage
a, Sanger sequencing showing the ELL3 vairations in the POC, father and mother from eight miscarriage families. Arrows indicating the positions of the variations. b, Capillary electrophoregrams illustrating the variability of STR markers across the 8 families. In the electrophoregrams, the bolded capitalized numbers/letters positioned above the peaks denoting the STR locus. X-axis representing the base pair length of the PCR products, whereas the y-axis corresponding to fluorescence intensity of these PCR products. Additionally, Ht signifying the peak height value, which aids in computing the peak height ratio for two alleles.
