Extended Data Fig. 4: The heteronuclear metal ion center in Cte 1 intron and comparison to canonical group II introns and spliceosome.
From: Structural basis of circularly permuted group II intron self-splicing
a-c. The cryo-EM maps and models depicting the heteronuclear metal ion center showing EBS-IBS interactions in a. pre-1S, b. 1S, c. 2S, d-f. 3′-SS interaction network in d. post-2S, e. chimeric O.i intron lariat (5J02), f. E.r. intron RNP post-2F (8T2T), and homology to g. E.r. intron RNP pre-1F (8T2S), h. E.r. intron RNP pre-2F (8T2R), i. yeast S. cerevisiae spliceosome C complex (7B9V). Black dashed lines indicate metal ion coordination, blue dashed lines indicate hydrogen bonds, arrows indicate nucleophilic attacks, and base stackings are highlighted in red.
