Extended Data Fig. 5: Cryo-EM analysis of THIK1 S136P.
From: Gating mechanism of the two-pore-domain potassium channel THIK1
a, cryo-EM data processing steps in Relion 4.0 and cryoSPARC4.4.1. See Methods for details. b, A representative cryo-EM micrograph of THIK1S136P. Scale bar, 200 Å. c, 2D class average images of THIK1S136P. d, Local resolution distribution for the density map of THIK1S136P. e, Euler angle distribution of the set of particles that contributed to the final density map of THIK1S136P. f, The GSFSC curve for the reconstruction of THIK1S136P. g, Cryo-EM densities for various TMs in the THIK1S136P.
