Supplementary Figure 6: Intra-plex correlations calculated on human+mouse and human-specific proteins and phosphorylation sites. | Nature Protocols

Supplementary Figure 6: Intra-plex correlations calculated on human+mouse and human-specific proteins and phosphorylation sites.

From: Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography–mass spectrometry

Supplementary Figure 6

The box-whisker plots depict Pearson correlations of TMT ratios between intraplex replicate measurements, separated into human+mouse and human-specific. A) Intraplex correlations of human+mouse and B) human-specific proteins. C) Intraplex correlations of human+mouse and B) human-specific phosphorylation sites. Focusing on proteins and phosphorylation sites with human origin resulted in lower intraplex variability. PDX models used in this study were approved by the institutional animal care and use committee at Washington University in St. Louis

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