Supplementary Figure 4: Analytical trace (RAD top, 282 nm UV bottom) of [18F]FDOPA 4 h post-end-of-synthesis.

Column: Luna NH2 5 micron 4.6 × 150 mm column; mobile phase: 70% MeCN 10 mM KOAc, pH 5.2; flow rate: 1.5 mL/min. [18F]FDOPA prepared using alternative synthesis with HLB purification between fluorination and deprotection.