Extended Data Fig. 4: Showing correlation (MiniTab v19) of the ND50 values of panel of 37 convalescent human sera tested in both PRNT and PNA. | Nature Protocols

Extended Data Fig. 4: Showing correlation (MiniTab v19) of the ND50 values of panel of 37 convalescent human sera tested in both PRNT and PNA.

From: Quantification of SARS-CoV-2 neutralizing antibody by wild-type plaque reduction neutralization, microneutralization and pseudotyped virus neutralization assays

Extended Data Fig. 4

The two assays show good correlation (Pearson correlation r= 0.862; p < 0.001) given that the PRNT is a wild-type virus assay performed at BSL3 with plaques as readout and the other is performed at BSL2 with a pseudotyped virus with a luminescent readout.

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