Extended Data Fig. 1: Comparison of sonication and cryo-bead milling methods for lysis of C. elegans.
From: Large-scale growth of C. elegans and isolation of membrane protein complexes
Representative FSEC trace of affinity purified TMC-2-mVenus isolated from worms that were either lysed with cryo-bead milling (black traces) or sonication (blue traces). Data from three separate worm harvests are shown to illustrate that cryo-bead milling reproducibly results in a higher ratio of TMC-2 dimer to monomer.
