Extended Data Fig. 8: Experimental setup for compound 7 (section 1). a-e) Small-scale reaction in a screw cap vial.
From: Synthesis of bicyclo[3.1.1]heptanes, meta-substituted arene isosteres, from [3.1.1]propellane
a) Screw cap vial with a magnetic stirrer bar, iodomethyl pivalate and fac-Ir(ppy)3 catalyst, b) Reaction vial connected to the Schlenk line by a needle, c) Purging of the reaction mixture, d) Reaction vial on a photo reactor, and e) After the reaction (~5 h stirring). f-i) Preperative-scale reaction in a one-neck round-bottomed flask. f) Flask, magnetic stirrer bar, and Subaseal, g) Flask connected to the Schlenk line by a needle, h) After addition of [3.1.1]propellane solution and pivalonitrile, and i) After the photochemical reaction.
