Table 1 Cohort demographic, endocrine, histopathological and radiological parameters.

Demographics

Mean age (range)

52.3 years (17 - 86)

Female: male

66: 70

Endocrine

Functional status

Functional = 50

(Acromegaly = 22

Cushing’s disease = 16

Prolactinoma = 12)

Non-functional = 85

N/A = 1

Macro: micro

114: 22

Histopathology

Ki-67

Low / < 3 = 105

3–5 = 18

6+ = 3

N/A or negative stain = 10

Cell type

Gonadotroph = 65

Corticotroph = 19

Somatotroph = 15

Lactotroph = 10

Mammosomatroph = 6

Thyrotroph = 2

Mixed = 2

Negative = 16

Cell lineage

SF1 = 66

PIT-1 = 33

TPIT = 19

Negative/null = 16

Mixed = 2

Radiomics

Mean tumor volume (mm³) [range]

6126 [200–57000]