Fig. 1
Diversity of spheroid morphology based on cell type. (A) Scatter plot of the first two principal components shows the diversity in spheroid morphology between cell types. Each dot represents a spheroid. (B) Loading plot of PCA shows underlying relationship between AnaSP spheroid morphology metrics and how the metrics steer the direction of the principal components. (C) PCA scatter plot of the cell types morphology metric averages, supported by illustrative spheroid images. Visualized cell types (9 out of 11) are indicated on the spheroid image. Scale bar = 200 µm, representative for all images. Note: 1 A describes all data, 1 C averages; as a consequence, scales and PC values differ slightly.
