Fig. 3

Three ccRCC samples were merged by Signac. (a) A total of 18,703 nuclei were unbiased clustering and classified into 20 different cell subtypes, which were projected by UMAP. (b) Spatial distribution of three different ccRCC samples on UMAP. (c–e) The chromatin accessibility of three different samples on chr 3, chr 9 and chr 17 were randomly selected to demonstrate.