Fig. 3

Scheme summarising the classification pipeline of (a) Method-2016 and (b) Method-2021, with the characteristics of their intermediate datasets, and (c) reporting the final dimensions of the updated elements of the simplified adult glioma classes. Each step indicates the number of samples involved in the classification procedure. Abbreviations: Astro, Astrocytoma; 7 + /10−, concomitant chromosome 7 gain/10 loss; GBM, glioblastoma; Histo, Histologic features; IDH, isocitrate dehydrogenase; LGG, Low Grade Glioma; Mix, Mixed-glioma (i.e. oligoastrocytoma); mut, mutant; NA, not available; Oligo, oligodendroglioma; TERT, Telomerase reverse transcriptase; WHO, World Health Organization; wt, wildtype.