Fig. 2

Cell clustering and identification of scRNA-Seq samples. (a) Visualization of seven main clusters across 100,387 cells using uniform manifold approximation and projection (UMAP). (b) Dot plot illustrating the normalized expression level of cell type-specific marker genes across SF clusters. The dots’ size and color spectrum indicate positive percentage and average expression (log1p transformed) of particular markers genes in each cell type, respectively. (c) Visualization of cells based on the treatment status of samples by using UMAP. BT, before treatment; AT, after treatment.