Figure 6 | Scientific Reports

Figure 6

From: Resistance to anticoagulant rodenticides in Martinique could lead to inefficient rodent control in a context of endemic leptospirosis

Figure 6

Resistance factors towards various ARs molecules of mutated VKORC1 detected in trapped rodents on Martinique Island. Resistance factor correspond to the ratio between Ki for mutated VKORC1 and wild type VKORC. Ki was the inhibition constant determined by expressing and characterising the susceptibility to AR of the recombinant mutated or non mutated VKORC1 enzyme. First-generation AR = WARF, warfarin; CHL, chlorophacinone. Second-generation AR = BROMA, bromadiolone; DFC, difenacoum; BFC, brodifacoum; DFT, difethialone. The dashed lines correspond to the resistance factor of 1, 5 and 10.

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