Table 2 Performance assessment of 2018 EFP/AAP and 2012 CDC/AAP case definitions on full-mouth PRPs. Measures presented as percentage with the correspondent 95% CI.

From: The 2018 periodontitis case definition improves accuracy performance of full-mouth partial diagnostic protocols

 

Ramfjord Teeth

CPITN Teeth

MB-B

MB-B-DB

MB-B-DL

Sensitivity

2018 EFP/AAP

63.2 (62.0–64.3)

87.1 (86.3–87.9)

69.3 (68.2–70.4)

79.1 (78.1–80.0)

84.9 (84.0–85.7)

2012 CDC/AAP

40.5 (39.4–41.7)

41.5 (40.4–42.7)

49.6 (48.4–50.7)

64.0 (62.9–65.1)

72.9 (71.9–74.0)

Specificity

2018 EFP/AAP

95.2 (94.7–95.7)

78.5 (77.5–79.5)

93.0 (92.4–93.6)

91.0 (90.4–91.7)

90.8 (90.2–91.5)

2012 CDC/AAP

99.9 (99.8–100.0)

99.8 (99.7–99.9)

99.9 (99.8–100.0)

99.4 (99.2–99.6)

99.1 (98.8–99.3)

Accuracy

2018 EFP/AAP

85.8 (85.0–86.6)

81.0 (80.1–82.0)

86.1 (85.3–86.9)

87.5 (86.7–88.3)

89.1 (88.4–89.8)

2012 CDC/AAP

65.9 (64.7–67.0)

66.4 (65.3–67.5)

71.1 (70.0–72.1)

79.1 (78.2–80.1)

84.1 (83.2–85.0)

Precision

2018 EFP/AAP

84.5 (83.7–85.4)

62.7 (61.6–63.9)

80.5 (79.6–81.5)

78.5 (77.6–79.5)

79.4 (78.4–80.3)

2012 CDC/AAP

99.8 (99.6–99.9)

99.6 (99.5–99.8)

99.8 (99.7–99.9)

99.3 (99.1–99.5)

99 (98.8–99.3)

Youden’s index

2018 EFP/AAP

58.4 (57.2–59.5)

65.6 (64.5–66.8)

62.3 (61.2–63.5)

70.1 (69.0–71.2)

75.7 (74.7–76.7)

2012 CDC/AAP

40.4 (39.2–41.5)

41.3 (40.2–42.5)

49.4 (48.3–50.6)

63.4 (62.3–64.6)

72.0 (70.9–73.0)

Diagnostic Odds Ratio (DOR)

2018 EFP/AAP

1.53 (1.37–1.69)

1.39 (1.25–1.54)

1.48 (1.34–1.62)

1.58 (1.44–1.73)

1.75 (1.59–1.9)

2012 CDC/AAP

2.7 (1.72–3.69)

2.54 (1.74–3.35)

2.86 (1.88–3.84)

2.49 (2.01–2.97)

2.45 (2.07–2.83)

F1 Score

2018 EFP/AAP

72.3 (71.3–73.4)

72.9 (71.9–74.0)

74.5 (73.5–75.5)

78.8 (77.8–79.8)

82.0 (81.1–82.9)

2012 CDC/AAP

57.6 (56.5–58.8)

58.6 (57.5–59.8)

66.2 (65.1–67.4)

77.9 (76.9–78.8)

84.0 (83.1–84.9)

Matthews Correlation Coefficient (MCC)

2018 EFP/AAP

64.2 (63.1–65.4)

60.8 (59.7–62.0)

65.3 (64.2–66.5)

70.0 (68.9–71.0)

74.3 (73.3–75.3)

2012 CDC/AAP

47.3 (46.1–48.4)

47.9 (46.8–49.1)

54.2 (53.0–55.4)

65.0 (63.9–66.1)

72.1 (71.1–73.2)

AUC (within ROC analysis)

2018 EFP/AAP

71.2 (70.1–72.3)

82.8 (81.9–83.7)

81.2 (80.3–82.1)

85.1 (84.2–85.9)

87.9 (87.1–88.6)

2012 CDC/AAP

70.2 (69.1–71.3)

70.7 (69.6–71.7)

74.7 (73.7–75.7)

81.7 (80.8–82.6)

86.0 (85.2–86.8)

  1. 95% CI – 95% Confidence Interval; AUC – Area Under the Curve; AAP – American Academy of Periodontology; B – Mid-buccal; CDC – Centers for Diseases Control; CPITN – Community Periodontal Index of Treatment Needs; DB – distal-buccal; DL – distal-lingual; EFP – European Federation of Periodontology; MB – Mesial-buccal; ROC – Receiver Operating Characteristic.
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