Table 1 Demographic and baseline characteristics of patients.
Characteristics | B-cell lymphoma (n = 9) | LPD (n = 12) | Others (n = 18) | P-value among all groups |
|---|---|---|---|---|
Age, years (range) | 72 (50–85) | 63 (35–81) | 69 (45–85) | 0.4281 |
Men (%) | 2 (22.2) | 4 (33.3) | 11 (61.1) | 0.1091 |
Smokers (current or ex-smoker) | 2 (22.2) | 6 (50.0) | 8 (44.4) | 0.1297 |
Serum levels | ||||
LDH, units/L (< 220) | 207 (160–364) | 231 (109–486) | 206 (130–1564) | 0.8941 |
sIL-2R, units/mL (< 500) | 676 (268–5590) | 776 (140–5117) | 822 (258–11,700) | 0.5968 |
Chest HRCT findings | ||||
Lung nodule and/or ground glass opacity | ||||
Solitary | 1 (11.1) | 1 (8.3) | 1 (5.5) | 0.8734 |
Multiple | 2 (22.2)* | 10 (83.3) | 9 (50.0) | 0.0190 |
Total | 3 (33.3) ‡ | 11 (91.6) | 10 (55.6) | 0.0193 |
Lung mass and/or airspace consolidation | ||||
Solitary | 4 (44.4) | 1 (8.3) | 4 (22.2) | 0.1502 |
Multiple | 3 (33.3) | 2 (16.7) | 4 (22.2) | 0.6641 |
Total | 7 (77.7) § | 3 (25.0) | 8 (44.4) | 0.0488 |
Hilar and/or mediastinal lymphadenopathy | 0 (0.0) | 4 (36.4) | 4 (21.1) | 0.1683 |
Bronchoalveolar lavage | ||||
Macrophages (%) | 62.0 (38.0–88.4) | 67.4 (20.9–86.3) | 68.7 (0–96.0) | 0.8614 |
Lymphocytes (%) | 24.0 (8.3–40.0) | 18.7 (8.3–76.5) | 18.3 (3.0–40.0) | 0.3428 |
Neutrophils (%) | 4.8 (1.0–44.0) | 2.0 (0.0–31.5) | 7.3 (0.0–49.0) | 0.2111 |
Eosinophils (%) | 0.0 (0.0–3.0) | 1.7 (0.0–12.6) | 1.0 (0.0–29.0) | 0.6291 |
Basophils (%) | 0.0 (0.0–0.0) | 0.0 (0.0–1.7) | 0.0 (0.0–0.0) | 0.3679 |
Lung biopsy | ||||
TBLB | 9 (100) | 11 (91.7) | 15 (83.3) | 0.3906 |
CT-guided | 0 (0.0) | 0 (0.0) | 1 (5.5) | 0.5495 |
SLB | 3 (33.3) | 2 (16.7) | 1 (5.5) | 0.1671 |
Other biopsies | ||||
Lip | 1 (11.1) | 2 (16.7) | 0 (0.0) | 0.2221 |
Bone | 1 (11.1) | 0 (0.0) | 0 (0.0) | 0.1808 |
TBNA | 0 (0.0) | 2 (16.7) | 1 (5.5) | 0.0933 |
Lymph node | 2 (22.2) | 3 (25.0) | 2 (11.1) | 0.5804 |
Subcutaneous nodule | 0 (0.0) | 1 (8.3) | 0 (0.0) | 0.3152 |
