Table 1 Immunization treatments.
Groups | RBD (µg/dose) | BLS (µg/dose) | Covalent coupling | RBD: BLS (molar ratio) | Adjuvant (Al(OH)3) |
|---|---|---|---|---|---|
RBD | 15 | 0 | –- | –- | No |
RBD | 15 | 0 | –- | –- | Yes |
RBD + BLS | 15 | 17 | No | 6.6:10 | No |
RBD-BLS LM | 15 | 70 | Yes | 1.5:10 | No |
RBD-BLS HM | 15 | 17 | Yes | 6.6:10 | No |
RBD-BLS HM | 15 | 17 | Yes | 6.6:10 | Yes |
