Figure 1

Genotypic frequencies of cytokines in NODAT and controls. Genotypes of cytokines are illustrated as homozygote (corresponded to high protein producer), heterozygote (corresponded to intermediate protein producer) and homozygote (corresponded to low protein producer). IL-6, IFNG and TGFB high producer genotypes were strongly associated with the disease, p = 0.05, 0.01 and 0.007; while, IL-4 high producer corresponded genotype was strongly associated with control cases, p = 0.001. In all cytokines intermediate protein level genotype did not show any significant association. Low protein producer corresponded genotypes were strongly associated with control group in IL-6, IFNG and TGFB, p = 0.05, 0.003 and 0.002; while, low protein level corresponded genotype in IL-4 was significantly associated with the disease, p = 0.001.