Table 1 Patient characteristics.

From: The ratio of T790M to EGFR-activating mutation predicts response of osimertinib in 1st or 2nd generation EGFR-TKI-refractory NSCLC

Characteristics

All patients n = 38

Age

Median (range)

68 (41—86)

Sex

Male/female

9/29

Smoking history

Never/ever

17/21

ECOG performance status

0/1/2

10/24/4

Histology

Adenocarcinoma/others

38/0

Sensitive EGFR mutation

19 deletion/L858R

20/18

The last EGFR-TKI

1st-G EGFR-TKIs/Afatinib

27/11

  1. 1st-G EGFR-TKIs: 1st-generation EGFR-TKIs; ECOG Eastern Cooperative Oncology Group.