Table 1 Donor and pre-liver transplantation recipient characteristics.

From: Liver transplantation for hepatocellular carcinoma using grafts from uncontrolled circulatory death donation

 

DBD group

uDCD group

p value

(n = 103)

(n = 41)

Donor characteristics

Mean age (y)

48 ± 13

41 ± 10

0.001

Sex

   

Male

68 (66%)

39 (95.1%)

0.004

Female

35 (34%)

2 (4.9%)

0.004

BMI (kg/m2)

24.2 ± 5.1

27.1 ± 5.4

0.040

Cardiac arrest

38 (39.6%)

41 (100%)

0.001

Vasopressor use

61 (59.2%)

41 (100%)

0.001

PRBC transfusion

25 (24.2%)

2 (4.8%)

0.089

Steatosis

   

No steatosis

54 (52.8%)

25 (60%)

0.500

Microsteatosis

11 (10.7%)

3 (7.3%)

0.604

Macrosteatosis < 30%

35 (34%)

12 (29.2%)

0.604

Cold ischemia time (min)

383 ± 156

371 ± 100

0.740

Recipient WIT (min)

60 (55–75)

60 (50–75)

0.121

Recipient characteristics

Mean age (y)

57 ± 8.1

61 ± 6.6

0.007

Sex

   

Male

87 (84.5%)

33 (80.5%)

0.361

Female

16 (15.5%)

8 (19.5%)

0.361

BMI (kg/m2)

28.5 ± 4.4

28.3 ± 4.6

0.804

OLT indications

HCV cirrhosis

70 (67.9%)

30 (73.1%)

0.344

HBV cirrhosis

16 (15.5%)

3 (7.3%)

0.148

Alcoholic cirrhosis

33 (32.1%)

11 (26.85)

0.344

Other diseases

2 (1.9%)

1 (2.4%)

0.492

MELD score

10 (8–14)

13 (9.5–18.5)

0.008

Comorbidities

Cardiac

11 (10.6%)

7 (17.1%)

0.302

Respiratory

9 (8.7%)

2 (4.8%)

0.302

Kidney

6 (5.8%)

4 (9.7%)

0.302

Laboratory values (pre-OLT)

Hemoglobin (g/dL)

12.6 ± 2.1

12.4 ± 2.3

0.618

Platelets (n × 103/mm3)

95 ± 49

76 ± 32

0.020

Prothrombin rate (%)

75 ± 18

63 ± 18

0.001

Bilirubin (mg/dL)

1.2 (0.6–2.7)

2.2 (1.3–3)

0.748

Serum creatinine (mg/dL)

0.8 (0.6–0.9)

0.8 (0.7–0.9)

0.767

Serum albumin (g/L)

3.6 (3–4.1)

3.2 (2.6–3.7)

0.215

  1. Italic values indicate statistically significant.
  2. AFP alpha-fetoprotein; BMI body mass index; DBD donation after brain death; HBV hepatitis B virus; HCV hepatitis C virus; MELD model for end stage liver disease; OLT orthotopic liver transplantation; PRBC packed red blood cells; uDCD uncontrolled donation after circulatory death; WIT warm ischemia time.
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