Figure 1 | Scientific Reports

Figure 1

From: Genotype–phenotype correlations for COL4A3COL4A5 variants resulting in Gly substitutions in Alport syndrome

Figure 1

Terminology used in this study to describe the position of Gly residues with respect to their local collagenous region. One single ‘local’ collagenous region is shown, bounded by non-collagenous interruptions at either end. The boxes could also represent either of the two non-collagenous termini. The non-collagenous boundary Gly residues are a special case, so were not included in this subgroup. The larger arrow indicates the direction of trimerisation, which is initiated at the carboxyl terminus and then proceeds in the amino direction. NC, non-collagenous.

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