Table 1 Characteristics of participants.

From: Association between serum free hemoglobin level and cerebral white matter hyperintensity volume in older adults

 

Total (n = 704)

Male (n = 277)

Female (n = 427)

p*

Age, years, mean (SD)

73.8 (6.6)

73.7 (6.8)

73.8 (6.5)

0.923

Hypertension, n (%)

372 (52.8)

142 (51.3)

230 (53.9)

0.500

Diabetes mellitus, n (%)

138 (19.6)

61 (22.0)

77 (18.0)

0.193

Stroke, n (%)

24 (3.4)

17 (6.2)

7 (1.6)

0.001

CIRS score, mean (SD)

6.5 (3.1)

6.9 (3.1)

6.1 (3.0)

0.001

Current drinking, n (%)

47 (6.7)

46 (16.6)

1 (0.2)

 < 0.001

Current smoking, n (%)

37 (5.3)

36 (13.0)

1 (0.2)

 < 0.001

SBP, mmHg, mean (SD)

128.9 (14.3)

128.7 (14.0)

129.0 (14.5)

0.773

DBP, mmHg, mean (SD)

75.9 (9.1)

76.3 (8.7)

75.6 (9.3)

0.361

BMI, kg/m2, mean (SD)

23.9 (2.9)

24.0 (2.8)

23.9 (2.9)

0.467

Cholesterol, mg/dL, mean (SD)

183.7 (37.7)

176.3 (35.6)

188.5 (38.2)

 < 0.001

HDL, mg/dL, mean (SD)

53.3 (13.5)

49.2 (12.1)

55.9 (13.6)

 < 0.001

GFR, mL/min, mean (SD)

79.4 (18.5)

76.9 (16.7)

81.0 (19.5)

0.003

Hemoglobin, g/dL, mean (SD)

13.7 (1.4)

14.5 (1.4)

13.1 (1.1)

 < 0.001

Anemia, n (%)

88 (12.5)

35 (12.6)

53 (12.4)

0.930

ICV, cc, mean (SD)

1508.8 (155.0)

1627.3 (137.4)

1431.8 (111.1)

 < 0.001

VWMH, cc, mean (SD)

11.0 (15.7)

12.8 (18.1)

9.8 (13.7)

0.020

VPVWMH, cc, mean (SD)

10.2 (15.4)

11.9 (17.8)

9.1 (13.5)

0.025

VDWMH, cc, mean (SD)

0.8 (2.2)

0.9 (3.2)

0.8 (1.2)

0.358

  1. CIRS cumulative illness rating scale, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, HDL high-density lipoprotein cholesterol, GFR glomerular filtration rate, ICV intracranial volume, VWMH volume of total white matter hyperintensity, VPVWMH volume of periventricular white matter hyperintensity, VDWMH volume of deep white matter hyperintensity.
  2. *Sex-differences by Student t-tests for continuous variables and chi-square tests for categorical variables.
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