Table 2 Individual effects of diabetes, BDNF Val66Met polymorphism, and tertiles of serum BDNF levels on acute and chronic suicidal ideation in patients with acute coronary syndrome.
Exposure | Group | Acute suicidal ideation | Chronic suicidal ideation | ||||||
|---|---|---|---|---|---|---|---|---|---|
N | No. (%) presence | OR (95% CI) | N | No. (%) presence | OR (95% CI) | ||||
Unadjusted | Adjusteda | Unadjusted | Adjusteda | ||||||
Diabetes | Absent | 778 | 148 (19.0) | 1.00 | 1.00 | 569 | 63 (11.1) | 1.00 | 1.00 |
Present | 191 | 47 (24.6) | 1.39 (0.96–2.02) | 1.11 (0.69–1.80) | 142 | 24 (16.9) | 1.63 (0.98–2.72) | 1.50 (0.86–2.62) | |
sBDNF | High | 323 | 60 (18.6) | 1.00 | 1.00 | 228 | 26 (11.4) | 1.00 | 1.00 |
Middle | 323 | 59 (18.3) | 0.98 (0.66–1.46) | 1.05 (0.65–1.70) | 249 | 34 (13.7) | 1.21 (0.71–2.08) | 1.37 (0.77–2.42) | |
Low | 323 | 76 (23.5) | 1.35 (0.92–1.97) | 1.73 (1.08–2.79)* | 234 | 27 (11.5) | 0.99 (0.56–1.75) | 1.04 (0.57–1.91) | |
BDNF genotype | Val/Val | 242 | 36 (14.9) | 1.00 | 1.00 | 173 | 18 (10.4) | 1.00 | 1.00 |
Val/Met | 498 | 106 (21.3) | 1.55 (1.02–2.34)* | 1.36 (0.83–2.25) | 378 | 47 (12.4) | 1.22 (0.69–2.18) | 1.07 (0.58–1.96) | |
Met/Met | 229 | 53 (23.1) | 1.72 (1.08–2.75)* | 1.40 (0.80–2.47) | 160 | 22 (13.8) | 1.37 (0.71–2.67) | 1.25 (0.63–2.51) | |
