Table 3 Univariate and multivariate analyses of risk factors with and OS in the training cohort.
Variables | HR (95% CI) | P value |
|---|---|---|
Univariate analyses | ||
Age (years) (> 60 vs. ≤ 60) | 1.470 (0.952, 2.270) | 0.083 |
Gender (male vs. female) | 0.851 (0.546, 1.326) | 0.476 |
BMI | 0.969 (0.928, 2.535) | 0.146 |
Child–Pugh classification (B and C vs. A) | 2.232 (0.927, 5.372) | 0.073 |
Alcohol consumption (yes vs. no) | 1.262 (0.812, 1.963) | 0.302 |
Hepatitis B (yes vs. no) | 0.284 (0.153, 0.525) | < 0.001 |
Hepatitis C (yes vs. no) | 1.078 (0.553, 2.104) | 0.825 |
Histologic grade (G3-4 vs. G1-2) | 0.922 (0.590, 1.439) | 0.720 |
Microvascular invasion (yes vs. no) | 1.527 (0.917, 2.543) | 0.103 |
AJCC tumor stage (III and IV vs. I and II) | 3.317 (2.084, 5.278) | < 0.001 |
Risk score | 2.714 (2.163, 3.405) | < 0.001 |
Multivariate analyses | ||
Hepatitis B (yes vs. no) | 0.451 (0.227, 0.894) | 0.023 |
AJCC tumor stage (III and IV vs. I and II) | 1.917 (1.154, 3.182) | 0.012 |
Risk score | 2.163 (1.670, 2.800) | < 0.001 |
