Table 4 Univariate and multivariate analyses of risk factors with and OS in the validation cohort.

From: Identification and validation of a novel pyroptosis-related lncRNAs signature associated with prognosis and immune regulation of hepatocellular carcinoma

Variables

HR (95% CI)

P value

Univariate analyses

Age (years) (> 60 vs. ≤ 60)

0.923 (0.507, 1.680)

0.794

Gender (male vs. female)

0.797 (0.436, 1.458)

0.461

BMI

1.023 (0.992, 1.055)

0.145

Child–Pugh classification (B and C vs. A)

0.967 (0.286, 3.274)

0.957

Alcohol consumption (yes vs. no)

0.558 (0.245, 1.267)

0.163

Hepatitis B (yes vs. no)

0.591 (0.270, 1.292)

0.188

Hepatitis C (yes vs. no)

1.051 (0.498, 2.221)

0.896

Histologic grade (G3-4 vs. G1-2)

1.778 (0.952, 3.323)

0.071

Microvascular invasion (yes vs. no)

1.156 (0.555, 2.407)

0.698

AJCC tumor stage (III and IV vs. I and II)

1.329 (0.691, 2.554)

0.393

Risk score

1.564 (1.200, 2.037)

0.001

Multivariate analyses

AJCC tumor stage (III and IV vs. I and II)

0.569 (0.628, 2.331)

0.569

Risk score

1.756 (1.208, 2.554)

0.003

  1. HR, hazard ratio; CI, confidence interval; OS, overall survival; BMI, body mass index; AJCC, American Joint Committee on Cancer.
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