Table 1 ACE2 variants (SNPs) detected in COVID-19 lean and obese patients. Eight exonic and intronic ACE2 variants were detected in the 82 COVID-19 subjects using Targeted-NGS.
From: ACE2 polymorphisms impact COVID-19 severity in obese patients
Variation | Consequence | EXON | INTRON | cDNA position | CDS position | Protein position | Amino acids | Codons | Existing variation |
|---|---|---|---|---|---|---|---|---|---|
X:g.15582209C > T | synonymous_variant | 18/19 | – | 2464 | 2247 | 749 | V | gtG/gtA | rs35803318 |
X:g.15582790C > T | intron_variant | – | 17/18 | – | – | – | – | – | rs2074192 |
X:g.15584429 T > A | synonymous_variant | 17/19 | – | 2278 | 2061 | 687 | A | gcA/gcT | COSV53023851 |
X:g.15586964C > T | intron_variant | – | 15/18 | – | – | – | – | – | rs4240157 |
X:g.15590807C > G | intron_variant | – | 12/18 | – | – | – | – | – | rs879922 |
X:g.15603635 T > C | missense_variant | 8/19 | - | 1080 | 863 | 288 | K/R | aAa/aGa | |
X:g.15608499 T > G | intron_variant | – | 5/18 | – | – | – | – | – | rs2048683 |
X:g.15610348C > T | splice_region | – | 4/18 | – | – | – | – | – | rs2285666, COSV53024795 |
