Table 2 Electrophysiological properties of early- and late-firing neurons.

From: The hyperexcitability of laterodorsal tegmentum cholinergic neurons accompanies adverse behavioral and cognitive outcomes of prenatal stress

 

Action potential (#)

AHP (mv)

First AP latency

First AP amplitude (mV)

First AP half-width (ms)

Control

Early-firing neurons

2.4 ± 0.4

P = 0.003**

F(2,24) = 9.2

10 ± 0.9

P = 0.17

F(2,24) = 3.4

29 ± 2.7

P = 0.004**

F(2,24) = 8.2

66.6 ± 1.3

P = 0.2

F(2,24) = 1.42

1.8 ± 0.06

P = 0.3

F(2,24) = 1.1

Late-firing neurons

1.4 ± 0.2

P = 0.009**

F(2,24) = 6.4

15.2 ± 09

P = 0.5

F(2,24) = 0.8

135.3 ± 12.2

P = 0.02*

F(2,24) = 6.8

66.3 ± 1.1

P = 0.2

F(2,24) = 1.7

2 ± 0.07

P = 0.2

F(2,24) = 1.4

Physical stress

Early-firing neurons

5.2 ± 0.6

12.2 ± 0.5

19.4 ± 0.9

64.8 ± 1.1

1.7 ± 0.04

Late-firing neurons

2.6 ± 0.2

16.6 ± 0.9

101.9 ± 4.2

64.6 ± 0.5

1.8 ± 0.08

Psychological stress

Early-firing neurons

4.5 ± 0.4

12.4 ± 0.5

21.5 ± 1.6

64.2 ± 1.1

1.7 ± 0.04

Late-firing neurons

2.6 ± 0.4

16.3 ± 0.7

102.2 ± 5.5

64.3 ± 0.7

1.8 ± 0.09

  1. AHP = Afterhyperpolarization. Data are represented as Mean ± SEM. * (p < 0.05), ** (p < 0.01) within groups.
  2. Significant values are in bold.
Back to article page