Table 5 Examining moderation of changes in Neuroticism by adverse life event experience and reexperience in the combined sample.

From: Prevalence and therapeutic impact of adverse life event reexperiencing under ceremonial ayahuasca

Moderator

Between baseline & post

Between baseline and 3-month follow-up

Sample size B

Timepoint B

Interaction Term B

Timepoint B

Interaction Term B

(A) Adverse life event experienced (full sample)

 Any ALE

− 0.51

− 0.02

− 0.41

− 0.07

312

 Any severe ALE

− 0.54

0.02

− 0.47

0.01

312

 Adverse life event index

− 0.49

− 0.02

− 0.41

− 0.02

312

(B) Adverse life event reexperienced (full sample)

 Any ALE

− 0.45

− 0.21***

− 0.39

− 0.19**

301

 Any severe ALE

− 0.50

− 0.18*

− 0.44

− 0.14

301

 Reexperiencing index

− 0.47

− 0.06***

− 0.42

− 0.05*

301

(C) Adverse life event reexperienced (only participants who endorsed previous ALE)

 Any ALE (combined sample)

− 0.46

− 0.18*

− 0.40

− 0.19*

259

 Any ALE (female sample)

− 0.38

− 0.24*

− 0.37

− 0.19

93

 Any ALE (male sample)

− 0.49

− 0.16*

− 0.41

− 0.19*

166

 Any severe ALE (combined sample)

− 0.47

− 0.17

− 0.41

− 0.16

170

 Reexperiencing index (combined sample)

− 0.48

− 0.05*

− 0.42

− 0.05*

259

  1. B = unstandardized coefficient. These results reflect eleven linear mixed effects models in which ALE experience and ALE reexperience variables were tested as moderators of the effect of Timepoint on Neuroticism (i.e., change in Neuroticism). Coefficients are unstandardized, and the Interaction Term coefficients represent the effect of interactions between each moderator and Timepoint on Neuroticism scores, (i.e., the estimated effect of a one-unit increase in the moderator on estimated change in Neuroticism between two timepoints). The moderators were unstandardized in these models.
  2. Section A reflects moderation of change in Neuroticism by ALE experience variables in the full sample. Section B reflects moderation of Neuroticism by ALE reexperience variables in the full sample. Section C reflects moderation of Neuroticism by ALE reexperience variables among only participants who endorsed previous ALE history. Results from two additional analyses are also included that focus on females and males separately. The effect of Timepoint was not inferentially interpreted.
  3. *p < 0.05, **p < 0.01, ***p < 0.005.