Table 1 Background characteristics of study participants by severity of COVID-19.

From: Clinical and laboratory characteristics of patients hospitalized with severe COVID-19 in New Orleans, August 2020 to September 2021

Total

Overall

Non-Severe

Severea

P valueb

N = 456

N = 269

N = 187

Age group, years

Range: [18–98] Median: 56

0.036

 18–44

112 (24.6%)

76 (28.3%)

36 (19.3%)

 45–64

214 (46.9%)

126 (46.8%)

88 (47.1%)

 ≥ 65

130 (28.5%)

67 (24.9%)

63 (33.7%)

Sex

0.592

 Female

197 (43.2%)

119 (44.2%)

78 (41.7%)

 Male

259 (56.8%)

150 (55.8%)

109 (58.3%)

Race and ethnicity

0.145

 Black, non-Hispanic

275 (60.3%)

169 (62.8%)

106 (56.7%)

 White, non-Hispanic

151 (33.1%)

88 (32.7%)

63 (33.7%)

 Hispanic

14 (3.1%)

5 (1.9%)

9 (4.8%)

 Other, non-Hispanicc

16 (3.5%)

7 (2.6%)

9 (4.8%)

Any underlying health conditionsd

0.188

 0

22 (4.8%)

15 (5.6%)

7 (3.7%)

 1

64 (14.0%)

32 (11.9%)

32 (17.1%)

 2

75 (16.4%)

50 (18.6%)

25 (13.4%)

 > 2

295 (64.7%)

172 (63.9%)

123 (65.8%)

Underlying health conditions

 Cardiac disease

279 (61.2%)

160 (59.5%)

119 (63.6%)

0.370

 Pulmonary disease

108 (23.7%)

67 (24.9%)

41 (21.9%)

0.461

 Neurologic disease

109 (23.9%)

69 (25.7%)

40 (21.4%)

0.294

 Renal disease

76 (16.7%)

35 (13.0%)

41 (21.9%)

0.012

 Liver disease

17 (3.7%)

8 (3.0%)

9 (4.8%)

0.308

 Immunocompromised

93 (20.4%)

60 (22.3%)

33 (17.6%)

0.225

 Diabetes mellitus

154 (33.8%)

89 (33.1%)

65 (34.8%)

0.710

 Hematological disease

58 (12.7%)

38 (14.1%)

20 (10.7%)

0.279

 Autoimmune disease

64 (14.0%)

35 (13.0%)

29 (15.5%)

0.450

 Smoking historye

140 (30.7%)

97 (36.1%)

43 (23.0%)

0.003

 Substance abuse history

88 (19.3%)

61 (22.7%)

27 (14.4%)

0.028

 Obesity

184 (40.4%)

91 (33.8%)

93 (49.7%)

< 0.001

 Endocrine disease

31 (6.8%)

18 (6.7%)

13 (7.0%)

0.913

 Gastrointestinal disease

87 (19.1%)

55 (20.4%)

32 (17.1%)

0.373

  1. aReceived high-flow (“ ≥ 6 L/min) nasal cannula/face mask (not able to distinguish) or were intubated, including subjects who died following high-flow/intubation.
  2. bPearson’s Chi-squared test.
  3. c“Non-Hispanic Other” refers to participants self-identifying as Asian, American Indian, other, or unknown.
  4. dRange [0–14]; All groups counted among “Underlying health conditions”.
  5. eCurrent or previous tobacco use.