Figure 3

A set of three miRNAs (miR-451a, miR-16, and miR-155) distinguishes G6PD-deficient individuals from normal controls. (A) ROC curve analysis of miR-451a, miR-16, and miR-155 levels. The sensitivity and specificity were calculated to determine the AUC with 95% confidence intervals (CIs). A P value < 0.05 was considered to indicate statistical significance. (B) A 3D scatter plot of the three miRNAs was generated using SPSS version 22 to identify patients with G6PD deficiency.