Table 2 Measured Values in Brain Regions.

From: Associations between diffusion kurtosis imaging metrics and neurodevelopmental outcomes in neonates with low-grade germinal matrix and intraventricular hemorrhage

ROI

Parameter

Neonates with low-grade GMH-IVH (n = 30)

Preterm neonates (n = 40)

P Value

FDR P value

PLIC

FA

0.486 ± 0.121

0.495 ± 0.131

0.483

0.526

MK

0.541 ± 0.134

0.623 ± 0.189

0.028*

0.093†

RK

0.704 ± 0.178

0.930 ± 0.241

 < 0.001***

0.012†

Thalamus

FA

0.181 ± 0.13

0.193 ± 0.22

0.493

0.537

MK

0.327 ± 0.073

0.431 ± 0.087

0.031*

0.093†

RK

0.411 ± 0.135

0.574 ± 0.106

0.045*

0.096†

GCC

FA

0.466 ± 0.04

0.479 ± 0.07

0.327

0.490

MK

0.507 ± 0.544

0.519 ± 0.387

0.629

0.629

RK

0.612 ± 0.373

0.644 ± 0.965

0.492

0.536

Caudate nucleus

FA

0.05 ± 0.03

0.06 ± 0.05

0.064

0.109

MK

0.454 ± 0.072

0.436 ± 0.098

0.052

0.103

RK

0.384 ± 0.088

0.416 ± 0.131

0.048*

0.096†

  1. Unless otherwise indicated, results are represented as mean ± standard deviation for continuous variables. Low-grade GMH-IVH low-grade GMH-IVH = low-grade Germinal Matrix Hemorrhage-Intraventricular Hemorrhage, FDR false discovery rate, ROI region of interest, PLIC posterior limbs of the internal capsule, GCC genu of corpus callosum, FA Fractional anisotropy, MK mean kurtosis, RK radial kurtosis.
  2. *P value < 0.05.
  3. ***P value < 0.001.
  4. †FDR P Value < 0.1.
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