Table 1 Summary of enzymatic and nonenzymatic electrochemical sensors studies for ascorbic acid detection.
Electrode + Material | Type | Linear range | Limit of detection (LOD) | Sensitivity | Method for sensitivity test | Selectivity | References |
|---|---|---|---|---|---|---|---|
Gold Nanodendrite/Screen-Printed Carbon Electrode | Non- enzymatic | 180–2700 μM | 16.8 μM | 0.0629 μA μM−1 or 1.5157 μA μM−1 cm−2 | Differential Pulse Voltammetry | Selective against uric acid, dopamine, glucose, and urea | This work |
Gold Nanoparticles/β-cyclodextrin/Graphene/ Glassy Carbon Electrode | Non- enzymatic | 30–2000 μM | 10.0 μM | 0.00921 μA μM−1 | Square Wave Voltammetry | Selective against uric acid and dopamine | |
Flower-like Au/Gold Electrode | Non- enzymatic | 60–500 μM | 10.0 μM | – | Differential Pulse Voltammetry | Selective against Ca2+, Mg2+, uric acid, glucose, glycine, and sodium citrate | |
Nanoflower-like Dendritic Au/Glassy Carbon Electrode | Non- enzymatic | 10–12,000 μM | 8.20 μM | 25.7 μA M−1 cm−2 | Constant Potential Amperometry | Selective against glucose and uric acid | |
Gold Nanoparticles/MoS2 Nanosheets/ Glassy Carbon Electrode | Non- enzymatic | 50 to 100,000 μM | 50.0 μM | – | Differential Pulse Voltammetry | Selective against uric acid and dopamine | |
Graphene Oxide/Poly(Aniline-Co-Thionine)/Glassy Carbon Electrode | Non- enzymatic | 500–5000 μM | 242 μM | 0.00199 μA μM−1 | Differential Pulse Voltammetry | Selective against glucose, sucrose, citric acid, and glycine | |
Ascorbate Oxidase/ Hydroxyapatite/Reduced Graphene Oxide/Gold Nanoparticles/Glassy Carbon Electrode | Enzymatic | 390–36,000 μM | 3.39 μM | 0.0159 μA μM−1 | Cyclic Voltammetry | Selective against sodium citrate, glucose, sucrose, and uric acid | |
Ascorbate Oxidase/Poly(ethylene glycol) (400) Diglycidyl Ether/Screen-Printed Carbon Electrode | Enzymatic | 5–150 μM | 3.00 μM | 0.0135 μA μM−1 | Constant Potential Amperometry | N/A | |
Ascorbate Oxidase/Poly(3,4-Ethylenedioxythiophene)/Multi-Walled Carbon Nanotubes/Pt Disc Electrode | Enzymatic | 50–20,000 μM | 15.0 μM | 0.0240 μA μM−1 cm−2 | Constant Potential Amperometry | Selective against fructose, glucose, sucrose, citric acid, L-alanine, ethanol, sodium chloride, oxalic acid, inositol, and nicotinic acid |