Table 1 Baseline patient characteristics.
Characteristics | Placebo (n = 14) | Heparin (n = 13) | P value |
---|---|---|---|
Age (years) | 55 (16.1) | 50 (12.6) | 0.3788* |
Height (cm) | 167 (11.2) | 162.92 (12) | 0.3702* |
Weight (kg) | 90.57 (16.7) | 79.85 (24.1) | 0.1884* |
BMI (kg/m2) | 32.80 (7.4) | 29.62 (7.3) | 0.2712* |
Days of symptoms | 12 (5.75) | 10 (4) | 0.3508** |
Vaccinated (2nd dose) | 0 (0) | 0 (0) | 0.9999# |
Gender | 0.4495# | ||
Male | 8 (57.1) | 5 (38.5) | |
Women | 6 (42.9) | 8 (61.5) | |
Ethnicity | 0.4815# | ||
White | 12 (85.7) | 13 (100) | |
Black | 2 (14.3) | 0 (0) | |
Behavioural factors | |||
Sedentary lifestyle | 12 (85.7) | 10 (76.9) | 0.6483# |
Smoking | 1 (7.1) | 2 (15.4) | 0.5956# |
Ex-smoking | 2 (14.3) | 4 (30.8) | 0.3845# |
Alcoholism | 0 (0) | 2 (15.4) | 0.2222# |
Comorbidity | |||
Systemic arterial hypertension | 9 (64.3) | 6 (46.2) | 0.4495# |
Coronary heart disease | 2 (14.3) | 2 (15.4) | 0.9999# |
Non-coronary heart disease | 2 (14.3) | 1 (7.7) | 0.9999# |
Dyslipidaemia | 5 (35.7) | 10 (76.9) | 0.0542# |
Cerebrovascular ischemic events | 1 (7.1) | 1 (7.7) | 0.9999# |
Neoplasm | 0 (0) | 0 (0) | 0.9999# |
Kidney transplant or immunosuppression | 3 (21.4) | 3 (23.1) | 0.9999# |
Autoimmune disease | 0 (0) | 1 (7.7) | 0.4815# |
Pneumopathy | 1 (7.1) | 2 (15.4) | 0.5956# |
Hypothyroidism | 0 (0) | 2 (15.4) | 0.2222# |
Depression | 2 (14.3) | 0 (0) | 0.4815# |
Concomitant antibiotics | 5 (35.7) | 5 (38.5) | 0.9999# |
Ceftriaxone 2000 mg/d | 1 (7.1) | 3 (23.1) | 0.3259# |
Azithromycin 500 mg/d | 1 (7.1) | 0 (0) | 0.9999# |
Cefepime 6000 mg/d | 2 (14.3) | 0 (0) | 0.4815# |
Amoxicillin + Clavulanate 1500 + 300 mg/d | 1 (7.1) | 2 (15.4) | 0.5956# |
Concomitant Dexamethasone 6 mg IV/d | 14 (100) | 11 (84.6) | 0.2222# |