Table 2 Comparison between daughters and parents with normal glucose tolerance.

From: The different associations of serum gamma-glutamyl transferase and alanine aminotransferase with insulin secretion, β-cell function, and insulin resistance in non-obese Japanese

 

Daughters

Parents

p values

n = 161

n = 83

Age (years)

20.4 ± 1.0

49.4 ± 4.3

< 0.001

BMI (kg/m2)

20.8 ± 2.4

22.6 ± 4.9

0.002

Fasting glucose (mg/dL)

83 ± 6

88 ± 7

< 0.001

30-min glucose (mg/dL)

121 ± 23

130 ± 27

0.004

1-h glucose (mg/dL)

100 ± 28

126 ± 36

< 0.001

2-h glucose(mg/dL)

90 ± 18

103 ± 18

< 0.001

Fasting insulin (μU/mL)

5.8 ± 3.0

5.0 ± 3.2

0.054

30-min insulin (μU/mL)

54 ± 32

42 ± 29

0.003

1-h insulin (μU/mL)

42 ± 25

49 ± 62

0.333

2-h insulin (μU/mL)

36 ± 23

35 ± 30

0.700

ΔGlucose30 (mg/dL)

37 ± 22

43 ± 25

0.091

ΔInsulin30 (μU/mL)

49 ± 31

37 ± 28

0.004

HbA1c (%)

5.2 ± 0.2

5.4 ± 0.3

< 0.001

HOMA-IR

1.2 ± 0.6

1.1 ± 0.8

0.276

Matsuda index

9.6 ± 4.3

11.8 ± 6.8

0.010

Disposition index

20 ± 53

15 ± 29

0.369

AUCg (mg/dL/2 h)

201 ± 35

233 ± 41

< 0.001

AUCi (µU/mL/2 h)

78 ± 36

77 ± 71

0.783

AST (U/L)

19 ± 6

21 ± 7

0.018

ALT (U/L)

14 ± 6

21 ± 11

< 0.001

GGT (U/L)

14 ± 4

27 ± 35

0.001

  1. Mean ± SD. ΔGlucose30 and ΔInsulin30: incremental glucose and insulin concentrations during the first 30 min of OGTT, respectively. Other abbreviations are the same as in Table 1.